The Insulin Receptor: A New Target for Cancer Therapy
نویسندگان
چکیده
منابع مشابه
The Insulin Receptor: A New Target for Cancer Therapy
A large body of evidences have shown that both the IGF-I receptor (IGF-IR) and the insulin receptor (IR) play a role in cancer development and progression. In particular, IR overactivation by IGF-II is common in cancer cells, especially in dedifferentiated/stem-like cells. In spite of these findings, until very recently, only IGF-IR but not IR has been considered a target in cancer therapy. Alt...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2011
ISSN: 1664-2392
DOI: 10.3389/fendo.2011.00093